Article
Identification of Androgen Response Elements in the Insulin-Like Growth Factor I Upstream Promoter
16 Mar 2007
Abstract excerpt
Testosterone stimulates the expression of IGF-I in cells and tissues that include prostate, muscle and muscle satellite cells, and the uterus. Here, the molecular mechanisms of this effect of testosterone were explored. Testosterone increased IGF-I mRNA levels in HepG2 and LNCaP cells and stimulated the activity of reporter genes controlled by 1.6 kb of the upstream promoter of the human IGF-I gene. An...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
