Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of leukemia inhibitory factor during mammalian development.

European cytokine network - 1 Dec 1996

Shellard J, Perreau J, Brûlet P

Abstract excerpt

Leukemia inhibitory factor (LIF) is a cytokine that exhibits proliferative, survival and differentiation activities on a wide range of cell types. A role for LIF in embryonic development is suggested by: i) its ability to stimulate the proliferation of embryonic stem (ES) cells in vitro, while maintaining their totipotency and ii) by both its maternal and embryonic expression at the time of blastocyst...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, CD
Share to Gene Expression Regulation, Developmental
Share to Interleukin-6

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Lymphokines

Share to Membrane Glycoproteins

Share to Mice, Transgenic

Share to Mutation

Source

Identifiers

PMID: 9010672

Genes

LIF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of leukemia inhibitory factor during mammalian development.PMID 9010672Read ↗

Leukemia Inhibitory Factor in Human ReproductionSemantic proximity Read ↗

LIF-Dependent Signaling: New Pieces in the LegoSemantic proximity Read ↗

Inhibited gastrulation in mouse embryos overexpressing the leukemia inhibitory factor.Semantic proximity Read ↗

Leukemia Inhibitory Factor and Human Embryo ImplantationSemantic proximity Read ↗

p53 regulates maternal reproduction through LIF.Semantic proximity Read ↗

Paracrine Induction of Stem Cell Renewal by LIF-Deficient Cells: A New ES Cell Regulatory PathwaySemantic proximity Read ↗

Cytokine signalling in embryonic stem cellsSemantic proximity Read ↗

Leukemia inhibitory factor and interleukin-11: critical regulators in the establishment of pregnancy.Semantic proximity Read ↗

Genetic reduction of embryonic leukemia-inhibitory factor production rescues placentation in SOCS3-null embryos but does not prevent inflammatory diseaseSemantic proximity Read ↗

Localization of Leukemia Inhibitory Factor and Its Receptor in Human Placenta Throughout Pregnancy1Semantic proximity Read ↗

Leukemia inhibitory factor and interleukin-11: cytokines with key roles in implantation.Semantic proximity Read ↗

LIF supports primitive endoderm expansion during pre-implantation development.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.