Article
Role of leukemia inhibitory factor during mammalian development.
European cytokine network - 1 Dec 1996
Shellard J, Perreau J, Brûlet P
Abstract excerpt
Leukemia inhibitory factor (LIF) is a cytokine that exhibits proliferative, survival and differentiation activities on a wide range of cell types. A role for LIF in embryonic development is suggested by: i) its ability to stimulate the proliferation of embryonic stem (ES) cells in vitro, while ma...
Topics
- Animals
- Antigens, CD
- Cytokine Receptor gp130
- Gene Expression Regulation, Developmental
- Growth Inhibitors
- Interleukin-6
- Leukemia Inhibitory Factor
- Leukemia Inhibitory Factor Receptor alpha Subunit
- Lymphokines
- Membrane Glycoproteins
- Mice
- Mice, Transgenic
- Mutation
- Receptors, Cytokine
- Receptors, OSM-LIF