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Article

Leukemia inhibitory factor and interleukin-11: critical regulators in the establishment of pregnancy.

Cytokine & growth factor reviews - 1 Aug 2009

Paiva Premila, Menkhorst Ellen, Salamonsen Lois, Dimitriadis Evdokia

Abstract excerpt

Blastocyst implantation into a receptive endometrium is critical to the establishment of pregnancy and is tightly regulated by factors within the blastocyst-endometrial micro-environment. Leukemia inhibitory factor (LIF) and interleukin-11 (IL11) have key roles during implantation. Female mice with a null mutation in the LIF or IL11RA gene are infertile due to a complete failure of implantation or a defective...

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Source

Identifiers

PMID: 19647472
DOI: 10.1016/j.cytogfr.2009.07.001

Genes

LIF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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