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Article

Localization of Leukemia Inhibitory Factor and Its Receptor in Human Placenta Throughout Pregnancy1

1 Feb 1999

Abstract excerpt

Mice in which the gene that encodes the receptor (R) for leukemia inhibitory factor (LIF) has been deleted show abnormal growth and development of the placenta. This indicates that LIF plays an important role in placental development. The expression of LIF-R and LIF was examined in human trophoblast and decidua using in situ hybridization and immunocytochemistry. LIF-R mRNA and immunoreactivity was localized in...

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PMID: 9916002
DOI: 10.1095/biolreprod60.2.355

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