Article
p21(WAF1/CIP1) response to genotoxic agents in wild-type TP53 expressing breast primary tumours.
Oncogene - 9 Jan 1997
Guillot C, Falette N, Paperin M P, Courtois S, Gentil-Perret A, Treilleux I, Ozturk M, Puisieux A
Abstract excerpt
Functional inactivation of the wild-type p53 protein has been described in different human cancers. Since a significant proportion of breast tumours express wild-type TP53, the p53 antiproliferative activity could be inactivated in transformed mammary epithelial cells by a mechanism independent o...
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