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Article

Characterization of human breast cancer cell lines for the studies on p53 in chemical carcinogenesis.

Toxicology in vitro : an international journal published in association with BIBRA - 1 Aug 2011

Huovinen Marjo, Loikkanen Jarkko, Myllynen Päivi, Vähäkangas Kirsi H

Abstract excerpt

To know whether the molecular responses to chemical carcinogens reflect only cell line specific molecular responses, or whether they can be regarded as characteristic of breast tissue, we have characterized four human breast cancer cell lines (MDA-MB-231, MDA-MB-468, T47-D, ZR-75-1). The activation of benzo(a)pyrene (BP), a model compound of polycyclic aromatic hydrocarbons, to its genotoxic BP-diolepoxide (BPDE)...

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Identifiers

PMID: 21457773
DOI: 10.1016/j.tiv.2011.03.018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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