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Article

p53 dependent cell-cycle arrest triggered by chemotherapy in xenografted breast tumors.

International journal of cancer - 15 Feb 2009

Varna Mariana, Lehmann-Che Jacqueline, Turpin Elisabeth, Marangoni Elizabetha, El-Bouchtaoui Morad, Jeanne Marion, Grigoriu Carmen, Ratajczak Philippe, Leboeuf Christophe, Plassa Louis-François, Ferreira Irmine, Poupon Marie-France, Janin Anne, de Thé Hugues, Bertheau Philippe

Abstract excerpt

The major long-term prognostic factor for breast cancer patients treated by first-line chemotherapy is response to treatment. We have previously shown that complete responses to high doses epirubicin-cyclophosphamide were observed only in human tumors bearing a TP53 mutation. Three xenografted hu...

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Identifiers

PMID: 19048622
DOI: 10.1002/ijc.24049

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19048622-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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