Article
Human GRB-IRbeta/GRB10. Splice variants of an insulin and growth factor receptor-binding protein with PH and SH2 domains.
The Journal of biological chemistry - 31 Jan 1997
Frantz J D, Giorgetti-Peraldi S, Ottinger E A, Shoelson S E
Abstract excerpt
cDNA clones encoding human (h) Grb7 and a previously unknown protein with high homology to hGrb-IR and mGrb10 (where m indicates mouse) were found by screening expressed sequence tag data bases. hGrb7 mRNA expression is greatest in pancreas and restricted to a few other tissues. The second protei...
Topics
- 3T3 Cells
- Alternative Splicing
- Amino Acid Sequence
- Animals
- Base Sequence
- Binding Sites
- Cloning, Molecular
- DNA Primers
- DNA, Complementary
- ErbB Receptors
- GRB10 Adaptor Protein
- GRB7 Adaptor Protein
- Gene Library
- Genetic Variation
- Humans
- Mice
- Molecular Sequence Data
- Muscle, Skeletal