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Article

p53 gene mutations are common in uterine serous carcinoma and occur early in their pathogenesis.

The American journal of pathology - 1 Jan 1997

Tashiro H, Isacson C, Levine R, Kurman R J, Cho K R, Hedrick L

Abstract excerpt

Uterine serous carcinoma (USC) is an uncommon but aggressive type of endometrial cancer associated with rapid progression of disease and a poor prognosis. Both USC and its recently described putative precursor, endometrial intraepithelial carcinoma (EIC), demonstrate strong p53 overexpression by immunohistochemistry, suggesting alteration of the p53 gene in their pathogenesis. In the present study, we evaluated...

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Identifiers

PMID: 9006334
PMCID: PMC1858541

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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