Article
Molecular identification of "latent precancers" for endometrial serous carcinoma in benign-appearing endometrium.
The American journal of pathology - 1 Jun 2009
Zhang Xi, Liang Sharon X, Jia Lin, Chen Ning, Fadare Oluwole, Schwartz Peter E, Kong Beihua, Zheng Wenxin
Abstract excerpt
Alteration of p53 is an early event in the development of endometrial serous carcinoma (ESC). We have recently identified a group of benign-looking endometria with p53 overexpression, designated "p53 signatures." In this study, we investigated these p53 signatures and evaluated whether they repre...
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