Article
TP53 Mutational Spectrum in Endometrioid and Serous Endometrial Cancers.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists - 1 Jul 2016
Schultheis Anne M, Martelotto Luciano G, De Filippo Maria R, Piscuglio Salvatore, Ng Charlotte K Y, Hussein Yaser R, Reis-Filho Jorge S, Soslow Robert A, Weigelt Britta
Abstract excerpt
Endometrial carcinomas (ECs) are heterogeneous at the genetic level. Although TP53 mutations are highly recurrent in serous endometrial carcinomas (SECs), these are also present in a subset of endometrioid endometrial carcinomas (EECs). Here, we sought to define the frequency, pattern, distribution, and type of TP53 somatic mutations in ECs by performing a reanalysis of the publicly available data from The Cancer...
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