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Article

Endometrial glandular dysplasia with frequent p53 gene mutation: a genetic evidence supporting its precancer nature for endometrial serous carcinoma.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Apr 2008

Jia Lin, Liu Yongjuan, Yi Xiaofang, Miron Alexander, Crum Christopher P, Kong Beihua, Zheng Wenxin

Abstract excerpt

PURPOSE: Endometrial glandular dysplasia (EmGD) has been recently proposed to be a putative precursor to endometrial serous carcinoma (ESC). The purpose of this study is to determine if EmGD is genetically linked to ESC and if it can be used for early detection. EXPERIMENTAL DESIGN: The tumor suppressor p53 gene was sequenced from serial samples of benign and neoplastic endometria with serous differentiation. The...

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Source

Identifiers

PMID: 18369088
DOI: 10.1158/1078-0432.CCR-07-4837

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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