Article
[Role of the p53 gene in apoptosis].
Nihon rinsho. Japanese journal of clinical medicine - 1 Jul 1996
Takahashi R, Shinohara H
Abstract excerpt
Cell numbers are controlled by a homeostatic mechanism between cell growth, arrest and programmed cell death (apoptosis) in normal and cancerous tissues. One of the tumor suppressor genes, p53, functions as a transcription factor or transcriptional regulator through DNA and protein binding properties, and plays an important role in regulating cell cycle and induction of apoptosis. Although there are two apoptotic...
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