Article
[Antioncogene p53 and apoptosis response: new hypotheses on the molecular bases of tumor resistance to radiotherapy].
La Radiologia medica - 1 Sept 1996
Corvò R
Abstract excerpt
Recent experimental data indicate that in normal or neoplastic cells, DNA damage induced by ionizing radiation may work as a signal to trigger apoptosis, a characteristic suicide program inherent to multicellular organisms. The morphological signatures of apoptosis are cell shrinkage, nuclear con...
Topics
- Apoptosis
- Cell Division
- Genes, p53
- Humans
- Mutation
- Necrosis
- Neoplasms
- Treatment Failure
- Tumor Suppressor Protein p53