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Article

The sensitivity of different analytical methods to detect disease susceptibility genes in rheumatoid arthritis sibling pair families.

The Journal of rheumatology - 1 Jan 1997

Marlow A, John S, Hajeer A, Ollier W E, Silman A J, Worthington J

Abstract excerpt

Our aim was to compare the sensitivity of 4 analytical methods to detect linkage to a known disease susceptibility locus, HLA-DRB1, in 100 rheumatoid arthritis sibling pair families with incomplete parental genotype information. Genotypes for the HLA-DRB1 and HLA-A loci were analyzed using (1) id...

Topics

Arthritis, Rheumatoid
Family Health
Female
Genes
Genetic Linkage
Genetic Predisposition to Disease
HLA-A Antigens
HLA-DR Antigens
Humans
Lod Score
Male
Methods

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Identifiers

PMID: 9002041

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9002041-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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