Article
Suppression of primary tumor growth and the progression to metastasis with p53 adenovirus in human prostate cancer.
The Journal of urology - 1 Sept 2000
Eastham J A, Grafton W, Martin C M, Williams B J
Abstract excerpt
PURPOSE: Numerous advances have been made in gene therapy approaches for the treatment of solid tumors, including prostate cancer. While treatment of the primary tumor has been well investigated, little information is available regarding gene therapy techniques which might impact on the progression to metastatic disease. We investigate the ability of p53 adenovirus to suppress not only primary tumor growth, but...
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