Article
Angiotensin I-converting enzyme gene polymorphism in non-diabetic renal disease.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Apr 2000
Samuelsson O, Attman P O, Larsson R, Mulec H, Rymo L, Weiss L, Ricksten A
Abstract excerpt
BACKGROUND: The insertion/deletion (I/D) polymorphism of the angiotensin-converting enzyme (ACE) gene determines the concentration of ACE in serum and local tissues. The role of this polymorphism in progressive chronic renal disease is still not fully clear. METHODS: We analysed the impact of the D/D polymorphism on the rate of decline in renal function in patients with non-diabetic, chronic progressive renal...
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