Article
Angiotensin-converting enzyme insertion/deletion polymorphism and diabetic albuminuria in patients with NIDDM followed Up for 9 years.
Nephron - 1 Sept 1998
Huang X H, Rantalaiho V, Wirta O, Pasternack A, Hiltunen T P, Koivula T, Malminiemi K, Nikkari T, Lehtimäki T
Abstract excerpt
Nephropathy is a major cause of premature morbidity and mortality in patients with non-insulin-dependent diabetes mellitus (NIDDM). The insertion/deletion (I/D) polymorphism of angiotensin-converting enzyme (ACE) is a genetic determinant of plasma ACE levels. Recent studies have found I/D polymor...
Topics
- Adult
- Aged
- Albuminuria
- Blood Pressure
- Cholesterol
- Cholesterol, HDL
- DNA Transposable Elements
- Diabetes Mellitus, Type 2
- Diabetic Nephropathies
- Follow-Up Studies
- Gene Frequency
- Genotype