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Article

Morphological alterations in the peripheral and central nervous systems of mice lacking glial cell line-derived neurotrophic factor (GDNF): immunohistochemical studies.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Feb 1997

Granholm A C, Srivastava N, Mott J L, Henry S, Henry M, Westphal H, Pichel J G, Shen L, Hoffer B J

Abstract excerpt

Glial cell line-derived neurotrophic factor (GDNF) is a member of the TGF-beta superfamily of growth factors with neurotrophic activity on midbrain dopaminergic neurons and on developing and mature motoneurons of the brainstem and spinal cord. To investigate the extent of GDNF dependency of central and peripheral nervous structures during development, we have performed an immunohistochemical analysis of sections...

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Source

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Identifiers

PMID: 8994069
PMCID: PMC6573173

Genes

GDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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