Article
Seizure-suppressor genes: can they help spearhead the discovery of novel therapeutic targets for epilepsy?
Expert opinion on therapeutic targets - 1 Jan 2000
Silva-Cardoso Gleice Kelli, N'Gouemo Prosper
Abstract excerpt
INTRODUCTION: Epilepsies are disorders of neuronal excitability characterized by spontaneously recurrent focal and generalized seizures, some of which result from genetic mutations. Despite the availability of antiseizure medications, pharmaco-resistant epilepsy is seen in about 23% of epileptic patients worldwide. Therefore, there is an urgent need to develop novel therapeutic strategies for epilepsies. Several...
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