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Article

The Drosophila erg K+ channel polypeptide is encoded by the seizure locus.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Feb 1997

Titus S A, Warmke J W, Ganetzky B

Abstract excerpt

The eag family of K+ channels contains three known subtypes: eag, elk, and erg. Genes representing the first two subtypes have been identified in flies and mammals, whereas the third subtype has been defined only by the human HERG gene, which encodes an inwardly rectifying channel that is mutated in some cardiac arrhythmias. To establish the predicted existence of a Drosophila gene in the erg subfamily and to...

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Identifiers

PMID: 8994042
PMCID: PMC6573166

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The Drosophila erg K+ channel polypeptide is encoded by the seizure locus.PMID 8994042Read ↗

The eag family of K+ channels in Drosophila and mammals.Semantic proximity Read ↗

The seizure locus encodes the Drosophila homolog of the HERG potassium channel.Semantic proximity Read ↗

The <i>Drosophila</i> ERG channel <i>seizure</i> plays a role in the neuronal homeostatic stress responseSemantic proximity Read ↗

Age-dependent electrical and morphological remodeling of the Drosophila heart caused by hERG/seizure mutations.Semantic proximity Read ↗

Identification of two nervous system-specific members of the erg potassium channel gene family.Semantic proximity Read ↗

Functional Analysis of a Mouse Brain Elk-Type K+ChannelSemantic proximity Read ↗

Molecular characterization of eag: a gene affecting potassium channels in Drosophila melanogaster.Semantic proximity Read ↗

Potassium channels in Drosophila: historical breakthroughs, significance, and perspectives.Semantic proximity Read ↗

Alteration of four identified K+ currents in Drosophila muscle by mutations in eag.Semantic proximity Read ↗

A Drosophila behavioral mutant, down and out (dao), is defective in an essential regulator of Erg potassium channels.Semantic proximity Read ↗

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Investigating Developmental and Epileptic Encephalopathy Using Drosophila melanogaster.Semantic proximity Read ↗

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