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The Drosophila<i>slamdance</i>Gene: A Mutation in an Aminopeptidase Can Cause Seizure, Paralysis and Neuronal Failure

1 Nov 2002

Abstract excerpt

We report here the characterization of slamdance (sda), a Drosophila melanogaster "bang-sensitive" (BS) paralytic mutant. This mutant exhibits hyperactive behavior and paralysis following a mechanical "bang" or electrical shock. Electrophysiological analyses have shown that this mutant is much more prone to seizure episodes than normal flies because it has a drastically lowered seizure threshold. Through genetic...

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PMID: 12454073
DOI: 10.1093/genetics/162.3.1283

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The Drosophila<i>slamdance</i>Gene: A Mutation in an Aminopeptidase Can Cause Seizure, Paralysis and Neuronal FailurePMID 12454073Read ↗

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