Article
The structure of human lupus anti-DNA antibodies.
Methods (San Diego, Calif.) - 1 Jan 1997
Zouali M
Abstract excerpt
B-cell hyperactivity and production of pathogenic autoantibodies are the main immunological events in the pathogenesis of the human autoimmune disease systemic lupus erythematosus. One approach to studying the pathogenesis of this disease and to understanding how the autoantibody response is initiated and sustained has been to analyze the variable genes expressed by antibodies that have the hallmarks of the...
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