[Genetic origins of anti-DNA autoantibodies].

Article

[Genetic origins of anti-DNA autoantibodies].

Annales de medecine interne - 1 Jan 1990

Eilat D

Abstract excerpt

A detailed analysis of variable region sequences, derived from monoclonal lupus anti-DNA autoantibodies has led to several conclusions with respect to the etiology and pathogenesis of systemic lupus erythematosus (SLE). It was found that the gene elements which are expressed in anti-DNA heavy and...

Topics

Animals
Antibodies, Antinuclear
Binding Sites, Antibody
Chemical Phenomena
Chemistry
Genes, Immunoglobulin
Humans
Lupus Erythematosus, Systemic
Mutation

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