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Article

Two autonomous nodules of a patient with multinodular goiter harbor different activating mutations of the thyrotropin receptor gene.

The Journal of clinical endocrinology and metabolism - 1 Jan 1997

Duprez L, Hermans J, Van Sande J, Dumont J E, Vassart G, Parma J

Abstract excerpt

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Topics

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Share to Adenoma
Share to Diagnosis, Differential
Share to DNA
Share to Goiter, Nodular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymerase Chain Reaction

Share to Receptors, Thyrotropin

Share to Sequence Analysis, DNA

Share to Thyroid Neoplasms

Source

Identifiers

PMID: 8989278
DOI: 10.1210/jcem.82.1.3691

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Two autonomous nodules of a patient with multinodular goiter harbor different activating mutations of the thyrotropin receptor gene.PMID 8989278Read ↗

Autonomous thyroid adenoma: only an adulthood disease?Semantic proximity Read ↗

Oncogenic mutations in the thyrotropin receptor of autonomously functioning thyroid nodules in the Japanese population.Semantic proximity Read ↗

Two novel mutations in the sixth transmembrane segment of the thyrotropin receptor gene causing hyperfunctioning thyroid nodules.Semantic proximity Read ↗

A novel activating mutation in the thyrotropin receptor gene in an autonomously functioning thyroid nodule developed by a Japanese patient.Semantic proximity Read ↗

Autonomously functioning thyroid nodules in a former iodine-deficient area commonly harbor gain-of-function mutations in the thyrotropin signaling pathway.Semantic proximity Read ↗

Diversity and prevalence of somatic mutations in the thyrotropin receptor and Gs alpha genes as a cause of toxic thyroid adenomas.Semantic proximity Read ↗

Identification of constitutively activating somatic thyrotropin receptor mutations in a subset of toxic multinodular goiters.Semantic proximity Read ↗

Does a Leu 512 Arg thyrotropin receptor mutation cause an autonomously functioning papillary carcinoma?Semantic proximity Read ↗

Screening of thyrotropin receptor mutations by fine-needle aspiration biopsy in autonomous functioning thyroid nodules in multinodular goiters.Semantic proximity Read ↗

A new silent germline mutation of the TSH receptor: coexpression in a hyperthyroid family member with a second activating somatic mutation.Semantic proximity Read ↗

Autonomous adenomas caused by somatic mutations of the thyroid-stimulating hormone receptor in children.Semantic proximity Read ↗

Activating Thyrotropin Receptor Mutations Are Present in Nonadenomatous Hyperfunctioning Nodules of Toxic or Autonomous Multinodular Goiter*Semantic proximity Read ↗

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