Article
Bacillus Calmette-Guérin mycobacteria stimulate human blood dendritic cells.
International journal of cancer - 6 Jan 1997
Thurnher M, Ramoner R, Gastl G, Radmayr C, Böck G, Herold M, Klocker H, Bartsch G
Abstract excerpt
Bacillus Calmette-Guérin (BCG) mycobacteria have been used as adjuvant in the active immunotherapy of various human cancers. In addition, dendritic cells, which are the most potent antigen-presenting cells, have been shown to be capable of initiating anti-tumor immune responses. Here we investiga...
Topics
- Antibodies, Monoclonal
- Antigens, CD
- B7-2 Antigen
- Cell Aggregation
- Cells, Cultured
- Dendritic Cells
- Flow Cytometry
- Humans
- Immunoglobulins
- Membrane Glycoproteins
- Mycobacterium bovis
- Phenotype
- Polymerase Chain Reaction
- RNA, Messenger
- Transcription, Genetic
- Tumor Necrosis Factor-alpha
- Up-Regulation
- CD83 Antigen