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Article

Dendritic cells cultured in anti-CD40 antibody-immobilized plates elicit a highly efficient peptide-specific T-cell response.

Journal of immunotherapy (Hagerstown, Md. : 1997) - 1 Jan 2000

Osada Takuya, Nagawa Hirokazu, Takahashi Tsuyoshi, Tsuno Nelson H, Kitayama Joji, Shibata Yoichi

Abstract excerpt

The function of dendritic cells (DCs), antigen-presenting cells that can initiate and regulate cellular and humoral responses, is highly influenced by their level of maturation. Immature DCs may be harmful in anti-tumor immunotherapy, because they can induce immunotolerance rather than immunostimulation. In this study, the authors sought to determine the optimal culture conditions for obtaining fully mature DCs....

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PMID: 12074047
DOI: 10.1097/00002371-200203000-00005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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