Article
Migratory sub-populations of afferent lymphatic dendritic cells differ in their interactions with Mycobacterium bovis Bacille Calmette Guerin.
Vaccine - 16 Mar 2012
Hope J C, Guzman E, Cubillos-Zapata C, Stephens S A, Gilbert S C, Prentice H, Sopp P, Howard C J, Charleston B
Abstract excerpt
Understanding how pathogens or vaccine antigens are targeted to dendritic cell (DC) subsets is important for disease pathogenesis studies and vaccine design. We characterised the sub-populations of migrating bovine DC with functional and phenotypic diversity present in pseudoafferent lymph draining the skin. These skin draining DC exist as a series of maturation dependent subsets with differential capacities for...
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