Creating conditional mutations in mammals.

doi:10.1016/0168-9525(96)10013-5

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Article

Creating conditional mutations in mammals.

Trends in genetics : TIG - 1 May 1996

Spencer D M

Abstract excerpt

For many years geneticists have relied on conditional activation to study the roles of cytolytic or cytostatic proteins in lower eukaryotes or to elucidate the epistatic relationships of proteins in a signaling pathway. Regardless of their merits, conditional mutants have only been available to m...

Topics

Animals
Gene Expression Regulation
Mammals
Mutation
Protein Processing, Post-Translational
Signal Transduction
Transcription, Genetic

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