Article
Recombinant human bone morphogenetic protein-2 maintains the articular chondrocyte phenotype in long-term culture.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society - 1 Nov 1996
Sailor L Z, Hewick R M, Morris E A
Abstract excerpt
Bone morphogenetic proteins have been shown to increase matrix synthesis by articular chondrocytes in short-term cultures. Members of this family of proteins have also been shown to induce endochondral ossification in vivo. The present study was performed to determine if the addition of human rec...
Topics
- Aggrecans
- Animals
- Animals, Newborn
- Bone Matrix
- Bone Morphogenetic Protein 2
- Bone Morphogenetic Proteins
- Cartilage, Articular
- Cattle
- Cell Division
- Cells, Cultured
- Collagen
- Extracellular Matrix Proteins
- Gene Expression
- Humans
- Lectins, C-Type
- Osteocalcin
- Phenotype
- Proteoglycans