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Article

Bone morphogenetic protein-2 facilitates expression of chondrogenic, not osteogenic, phenotype of human intervertebral disc cells.

Spine - 15 Dec 2003

Kim Dong-Jun, Moon Seong-Hwan, Kim Hyang, Kwon Un-Hye, Park Moon-Soo, Han Keong-Jin, Hahn Soo-Bong, Lee Hwan-Mo

Abstract excerpt

STUDY DESIGN: In vitro experiment using bone morphogenetic protein-2 (BMP-2) and human intervertebral disc (IVD) cells. OBJECTIVES: To demonstrate the effect of BMP-2 on mRNAs expression (collagen type I, collagen type II, aggrecan, and osteocalcin), proteoglycan synthesis, expression of alkaline phosphatase, bone nodule formation in human IVD cells. SUMMARY OF BACKGROUND DATA: BMP-2 was widely known as a...

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Source

Identifiers

PMID: 14673369
DOI: 10.1097/01.BRS.0000101445.46487.16

Genes

IVD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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