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Article

Osteogenin promotes reexpression of cartilage phenotype by dedifferentiated articular chondrocytes in serum-free medium.

Experimental cell research - 1 Feb 1991

Harrison E T, Luyten F P, Reddi A H

Abstract excerpt

Chondrocytes lose their phenotypic traits, including type II collagen, after serial passage in monolayer cultures. Osteogenin, a bone morphogenetic protein, induces cartilage and bone in nonskeletal sites. This investigation examined the ability of osteogenin to promote the reexpression of cartilage phenotype by dedifferentiated chondrocytes obtained from rabbit articular cartilage. The results revealed that...

Topics

Animals
Bone Morphogenetic Protein 3
Bone Morphogenetic Proteins
Cartilage, Articular
Cell Differentiation
Cell Division
Cells, Cultured
Collagen
Culture Media
Gene Expression Regulation
Growth Substances

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Proteins

Proteoglycans

Rabbits

Source

Identifiers

PMID: 1988283
DOI: 10.1016/0014-4827(91)90050-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1988283-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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