Article
Osteogenin promotes reexpression of cartilage phenotype by dedifferentiated articular chondrocytes in serum-free medium.
Experimental cell research - 1 Feb 1991
Harrison E T, Luyten F P, Reddi A H
Abstract excerpt
Chondrocytes lose their phenotypic traits, including type II collagen, after serial passage in monolayer cultures. Osteogenin, a bone morphogenetic protein, induces cartilage and bone in nonskeletal sites. This investigation examined the ability of osteogenin to promote the reexpression of cartilage phenotype by dedifferentiated chondrocytes obtained from rabbit articular cartilage. The results revealed that...
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