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Article

Recombinant bone morphogenetic protein-4, transforming growth factor-beta 1, and activin A enhance the cartilage phenotype of articular chondrocytes in vitro.

Experimental cell research - 1 Feb 1994

Luyten F P, Chen P, Paralkar V, Reddi A H

Abstract excerpt

Bone morphogenetic protein-4 (BMP-4) is a member of the transforming growth factor-beta (TGF-beta) supergene family and is characterized by its ability to induce singly de novo cartilage and bone in vivo. The influence of recombinant bone morphogenetic protein-4 and some related members, TGF-beta 1, activin A, and inhibin A, on articular chondrocyte metabolism in the presence and absence of extracellular matrix...

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Identifiers

PMID: 8299720
DOI: 10.1006/excr.1994.1033

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Recombinant bone morphogenetic protein-4, transforming growth factor-beta 1, and activin A enhance the cartilage phenotype of articular chondrocytes in vitro.PMID 8299720Read ↗

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Human osteogenic protein-1 induces both chondroblastic and osteoblastic differentiation of osteoprogenitor cells derived from newborn rat calvaria.Semantic proximity Read ↗

Phenotypic maintenance of articular chondrocytes in vitro requires BMP activity.Semantic proximity Read ↗

Transforming growth factor alpha suppression of articular chondrocyte phenotype and Sox9 expression in a rat model of osteoarthritis.Semantic proximity Read ↗

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Characterization of proteoglycans synthesized by rabbit articular chondrocytes in response to transforming growth factor-beta (TGF-beta).Semantic proximity Read ↗

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