Article
The nature of Reed-Sternberg cells: phenotype, genotype, and other properties.
Critical reviews in oncogenesis - 1 Jan 1994
Hsu S M, Hsu P L
Abstract excerpt
The most recent sophisticated investigations have provided new and revealing but also contradictory and controversial informaiton on the biological nature and the cellular origin of Hodgkin and Reed-Sternberg (H-RS) cells. Immunophenotypic analyses have shown consistent expression of CD15, CD30, CD74, and HLA-Dr antigens, but generally lack of T- or B cell-associated markers in H-RS cells. The H-RS cells are also...
Topics
- Gene Expression Regulation, Neoplastic
- Genotype
- Humans
- Phenotype
- Reed-Sternberg Cells