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Article

Function of the Evx-2 gene in the morphogenesis of vertebrate limbs.

The EMBO journal - 2 Dec 1996

Hérault Y, Hraba-Renevey S, van der Hoeven F, Duboule D

Abstract excerpt

Vertebrate gene members of the HoxD complex are essential for proper development of the appendicular skeletons. Inactivation of these genes induces severe alterations in the size and number of bony elements. Evx-2, a gene related to the Drosophila even-skipped (eve) gene, is located close to Hoxd-13 and is expressed in limbs like the neighbouring Hoxd genes. To investigate whether this tight linkage reflects a...

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PMID: 8978698
PMCID: PMC452496

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