Article
A global control region defines a chromosomal regulatory landscape containing the HoxD cluster.
Cell - 2 May 2003
Spitz François, Gonzalez Federico, Duboule Denis
Abstract excerpt
During limb development, coordinated expression of several Hoxd genes is required in presumptive digits. We searched for the underlying control sequences upstream from the cluster and found Lunapark (Lnp), a gene which shares limb and CNS expression specificities with both Hoxd genes and Evx2, an...
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