Article
Evx2-Hoxd13 intergenic region restricts enhancer association to Hoxd13 promoter.
PloS one - 24 Jan 2007
Yamagishi Takumi, Ozawa Michiru, Ohtsuka Chiho, Ohyama-Goto Ritsuko, Kondo Takashi
Abstract excerpt
Expression of Hox genes is tightly regulated in spatial and temporal domains. Evx2 is located next to Hoxd13 within 8 kb on the opposite DNA strand. Early in development, the pattern of Hoxd13 expression resembles that of Evx2 in limb and genital buds. After 10 dpc, however, Evx2 begins to be exp...
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