Microtubule-associated protein tau in human fibroblasts with the Swedish Alzheimer mutation.

doi:10.1016/s0304-3940(96)13218-3

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Article

Microtubule-associated protein tau in human fibroblasts with the Swedish Alzheimer mutation.

Neuroscience letters - 6 Dec 1996

Ingelson M, Vanmechelen E, Lannfelt L

Abstract excerpt

The principal neuropathological hallmarks of Alzheimer's disease (AD) are plaques containing amyloid beta peptide (Abeta) and tangles with hyperphosphorylated tau. Tau is predominantly found in the nervous system but has been reported in fibroblasts from individuals with and without AD. Abeta is...

Topics

Aged
Alzheimer Disease
Amyloid beta-Peptides
Humans
Middle Aged
Mutation
tau Proteins

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