Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Brahma-Related Gene 1-Dependent STAT3 Recruitment at IL-6-Inducible Genes

1 Jan 2007

Abstract excerpt

IL-6 is an immunoregulatory cytokine with multiple functions in hemopoiesis, proliferation, and tumorigenesis. IL-6 triggers phosphorylation, dimerization, and nuclear translocation of STAT3, which binds to target promoters and activates transcription. Brahma-related gene 1 (BRG1), the enzymatic engine of the yeast-mating type-switching and sucrose-nonfermenting chromatin-remodeling complex, is essential for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Mechanisms and Therapy
Share to Chromatin Remodeling and Cancer
Share to Cytokine Signaling Pathways and Interactions

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 17182572
DOI: 10.4049/jimmunol.178.1.345

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Brahma-Related Gene 1-Dependent STAT3 Recruitment at IL-6-Inducible GenesPMID 17182572Read ↗

Chromatin-remodelling factor BRG1 selectively activates a subset of interferon-alpha-inducible genes.Semantic proximity Read ↗

Distinct modes of action applied by transcription factors STAT1 and IRF1 to initiate transcription of the IFN-gamma-inducible gbp2 gene.Semantic proximity Read ↗

A switch from hBrm to Brg1 at IFNγ-activated sequences mediates the activation of human genesSemantic proximity Read ↗

T helper type 1–specific Brg1 recruitment and remodeling of nucleosomes positioned at the IFN-γ promoter are Stat4 dependentSemantic proximity Read ↗

SATB1 dictates expression of multiple genes including IL-5 involved in human T helper cell differentiationSemantic proximity Read ↗

Properties of STAT1 and IRF1 enhancers and the influence of SNPs.Semantic proximity Read ↗

<i>In Silico</i> Genomic Analysis of the Human and Murine Guanylate-Binding Protein (GBP) Gene ClustersSemantic proximity Read ↗

BRD9 is a druggable component of interferon-stimulated gene expression and antiviral activitySemantic proximity Read ↗

A Comprehensive Profile of ChIP-Seq-Based STAT1 Target Genes Suggests the Complexity of STAT1-Mediated Gene Regulatory MechanismsSemantic proximity Read ↗

Epigenetic signals that direct cell type–specific interferon beta response in mouse cellsSemantic proximity Read ↗

Isolation and characterization of a human STAT1 gene regulatory element. Inducibility by interferon (IFN) types I and II and role of IFN regulatory factor-1.Semantic proximity Read ↗

Asymmetric Action of STAT Transcription Factors Drives Transcriptional Outputs and Cytokine Specificity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.