Neuron-specific expression of the rat brain type II sodium channel gene is directed by upstream regulatory elements.

doi:10.1016/0896-6273(90)90097-y

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Article

Neuron-specific expression of the rat brain type II sodium channel gene is directed by upstream regulatory elements.

Neuron - 1 Feb 1990

Maue R A, Kraner S D, Goodman R H, Mandel G

Abstract excerpt

Genetic elements involved in cell-specific expression of the type II sodium channel gene were revealed using transient expression assays. A chimeric reporter gene containing 1051 bp of the sodium channel 5' flanking region was active in neuroblastoma and PC12 cells, but inactive in nonneuronal ce...

Topics

Animals
Base Sequence
Brain
Chimera
Gene Expression Regulation
Genes
Molecular Sequence Data
Muscles
Mutation
Neurons
Organ Specificity
Promoter Regions, Genetic
Rats
Regulatory Sequences, Nucleic Acid
Restriction Mapping
Sequence Homology, Nucleic Acid
Sodium Channels
Tumor Cells, Cultured

Source

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Identifiers

PMID: 2155009
DOI: 10.1016/0896-6273(90)90097-y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2155009-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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