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Article

Gs alpha mutation may be uncommon in patients with multiple endocrine neoplasia type 1.

The Journal of clinical endocrinology and metabolism - 1 Jun 1996

Sakurai A, Katai M, Furihata K, Hashizume K

Abstract excerpt

Activating mutations of the Gs alpha gene, termed gsp, have been identified in various endocrine tumors. Recently, a high frequency of gsp mutation in patients with multiple endocrinopathies was reported, and a family with both McCune-Albright syndrome and multiple endocrine neoplasia type 1 was described. Each suggests that the oncogenic mutations of Gs alpha may play an important role in tumorigenesis in...

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Source

Identifiers

PMID: 8964883
DOI: 10.1210/jcem.81.6.8964883

Genes

MEN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Gs alpha mutation may be uncommon in patients with multiple endocrine neoplasia type 1.PMID 8964883Read ↗

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G protein gene mutations in patients with multiple endocrinopathies.Semantic proximity Read ↗

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Activating mutations of the Gs alpha-gene in nonfunctioning pituitary tumors.Semantic proximity Read ↗

Activating mutation of the stimulatory G protein (gsp) as a putative cause of ovarian and testicular human stromal Leydig cell tumors.Semantic proximity Read ↗

Low prevalence of Gs alpha mutations in śomatotroph adenomas of children and adolescents.Semantic proximity Read ↗

Prevalence of Gs alpha mutations in Korean patients with pituitary adenomasSemantic proximity Read ↗

Two G protein oncogenes in human endocrine tumors.Semantic proximity Read ↗

Prevalence of three mutations in the Gs alpha gene among 24 families with pseudohypoparathyroidism type Ia.Semantic proximity Read ↗

Activating mutations of the Gs alpha gene are associated with low levels of Gs alpha protein in growth hormone-secreting tumors.Semantic proximity Read ↗

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