Novel MEN1 gene mutations in familial multiple endocrine neoplasia type 1.

doi:10.1007/s100380050070

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Article

Novel MEN1 gene mutations in familial multiple endocrine neoplasia type 1.

Journal of human genetics - 1 Jan 1998

Sakurai A, Shirahama S, Fujimori M, Katai M, Itakura Y, Kobayashi S, Amano J, Fukushima Y, Hashizume K

Abstract excerpt

The recent isolation of the gene responsible for multiple endocrine neoplasia type 1 (MEN 1) has enabled direct genetic diagnosis for people with endocrine tumors and family members of affected patients. Although MEN 1 is rarely recognized in the Japanese population compared to its prevalence in...

Topics

Frameshift Mutation
Germ-Line Mutation
Humans
Japan
Multiple Endocrine Neoplasia Type 1
Mutagenesis, Insertional
Mutation
Neoplasm Proteins
Prevalence
Proto-Oncogene Proteins
Sequence Deletion

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