Article
DQB1 promoter sequence variability and linkage in caucasoids.
Human immunology - 1 Dec 1996
Reichstetter S, Brünnler G, Kalden J R, Wassmuth R
Abstract excerpt
Sequence variability in the upstream regulatory regions (URR) of HLA class II genes has been described as an additional mechanism of diversity in these polymorphic genes. For HLA-DQB1, 12 URR variants have been identified previously by sequence analysis of approx. 600 bp located immediately upstream of the first exon of the DQB1 gene. To investigate the distribution of these promoter alleles and their linkage...
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