Article
Polymorphism in the upstream regulatory region of DQA1 genes and DRB1, QAP, DQA1, and DQB1 haplotypes in the German population.
Human immunology - 1 Jan 1994
Haas J P, Kimura A, Andreas A, Hochberger M, Keller E, Brünnler G, Bettinotti M P, Nevinny-Stickel C, Hildebrandt B, Sierp G
Abstract excerpt
Polymorphism in the URR of the MHC class II DQA1 gene defines ten different alleles named QAP. Oligotyping for the alleles of DRB1, QAP, DQA1, and DQB1 have been performed in 210 unrelated healthy controls from Germany. Moreover, 83 HTCs from the Tenth IHWS have been tested. Four point loci haplo...
Topics
- Alleles
- Base Sequence
- DNA
- DNA Primers
- Genes, Regulator
- Genotype
- Germany
- HLA-DQ Antigens
- HLA-DR Antigens
- Haplotypes
- Humans
- Linkage Disequilibrium
- Molecular Sequence Data
- Polymerase Chain Reaction
- Polymorphism, Genetic
