Article
Expression of Egr-1 correlates with the transformed phenotype and the type of viral latency in EBV genome positive lymphoid cell lines.
Oncogene - 21 Nov 1996
Calogero A, Cuomo L, D'Onofrio M, de Grazia U, Spinsanti P, Mercola D, Faggioni A, Frati L, Adamson E D, Ragona G
Abstract excerpt
In this paper we have investigated the role of Egr-1 in B cell growth regulation by examining the gene expression in a panel of B cell lines, including both EBV genome negative and EBV carrying cell lines. Egr-1 expression correlates with the cellular phenotype and the specific pattern of viral latency established within the individual cell lines. Thus, constitutive activation of Egr-1 gene is invariably...
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