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Article

SH2D1A expression in Burkitt lymphoma cells is restricted to EBV positive group I lines and is downregulated in parallel with immunoblastic transformation.

International journal of cancer - 1 Aug 2002

Nagy Noémi, Maeda Akihiko, Bandobashi Kentaro, Kis Loránd L, Nishikawa Jun, Trivedi Pankaj, Faggioni Alberto, Klein George, Klein Eva

Abstract excerpt

The SH2 domain containing SH2D1A protein has been characterized in relation to the X-linked lymphoproliferative disease (XLP), a primary immunodeficiency that leads to serious clinical conditions after Epstein-Barr virus (EBV) infection. The SH2D1A gene is mutated in the majority of XLP patients. We previously detected SH2D1A in activated T and NK cells, but not in B lymphocytes. We have found SH2D1A protein in...

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Identifiers

PMID: 12115526
DOI: 10.1002/ijc.10498

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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