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Article

EBV genome carrying B lymphocytes that express the nuclear protein EBNA-2 but not LMP-1

1 Feb 2013

Abstract excerpt

The potentially oncogenic Epstein-Barr virus (EBV) is carried by almost all humans in a well equilibrated coexistence. The phenotype of the cells that carry EBV genomes is determined by virally-encoded and cellular proteins. B lymphocyte is the main target of the virus and latent infection of this cell induces proliferation. Nine virus-encoded genes participate in the "growth program" that is expressed in a...

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PMID: 23526738
DOI: 10.4161/onci.23035

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