Article
Stem-cell organization in mouse small intestine.
Proceedings. Biological sciences - 23 Jul 1990
Winton D J, Ponder B A
Abstract excerpt
We have investigated stem-cell organization in mouse small intestine (SI) by using a cellular marker induced by somatic mutation. In small intestinal whole mounts from heterozygous Dlb-1b/Dlb-1a mice stained with a peroxidase conjugate of Dolichos biflorus agglutinin (DBA-Px), mutations of Dlb-1b in stem cells result in loss of DBA-Px binding and so are recognizable as wholly or partly unstained crypts. The...
Topics
- Animals
- Cell Division
- Epithelium
- Female
- Genetic Markers
- Intestine, Small
- Male
- Mice
- Mice, Inbred C57BL
- Mutation
- Stem Cells
