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Article

HGF receptor associates with the anti-apoptotic protein BAG-1 and prevents cell death.

The EMBO journal - 15 Nov 1996

Bardelli A, Longati P, Albero D, Goruppi S, Schneider C, Ponzetto C, Comoglio P M

Abstract excerpt

The mechanisms by which apoptosis is prevented by survival factors are largely unknown. Using an interaction cloning approach, we identified a protein that binds to the intracellular domain of the hepatocyte growth factor (HGF) receptor. This protein was identified as BAG-1, a recently characterized Bcl-2 functional partner, which prolongs cell survival through unknown mechanisms. Overexpression of BAG-1 in liver...

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Share to Carrier Proteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 8947043
PMCID: PMC452442

Genes

HGF

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HGF receptor associates with the anti-apoptotic protein BAG-1 and prevents cell death.PMID 8947043Read ↗

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