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Article

Debrisoquine and S-mephenytoin hydroxylation phenotypes and genotypes in a Korean population.

Pharmacogenetics - 1 Oct 1996

Roh H K, Dahl M L, Johansson I, Ingelman-Sundberg M, Cha Y N, Bertilsson L

Abstract excerpt

One hundred and fifty-two healthy Korean volunteers were phenotyped with debrisoquine and mephenytoin and genotyped with respect to CYP2D6. The debrisoquine metabolic ratio (MR) varied between 0.09 and 6.3, and all subjects were thus classified as extensive metabolizers of debrisoquine. Polymerase chain reaction (PCR)-based amplification of genomic DNA with primers specific for the C188-->T mutation present in...

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PMID: 8946476
DOI: 10.1097/00008571-199610000-00008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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